A graphic that depicts the immune-suppressive TME

The pancreatic cancer tumor microenvironment (TME). The figure depicts the immune-suppressive TME, which consists of myeloid-derived suppressor cells (MDSCs) and tumor-associated macrophages (TAMs). Also shown is the extracellular matrix, vasculature, cancer-associated fibroblasts (CAFs), and major cytokines that have been implicated in TME regulation.

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